Routine central compartment lymph node dissection for patients with papillary thyroid carcinoma.

نویسندگان

  • David I Kutler
  • Audrey D Crummey
  • William I Kuhel
چکیده

BACKGROUND The role of routine central compartment neck dissection in papillary thyroid cancer is controversial. METHODS A retrospective medical record review was conducted of 83 patients with papillary thyroid cancer who received either total or hemithyroidectomy and central compartment lymphadenectomy. RESULTS Positive central compartment node metastases were found in approximately equal rates between older and younger patients (38.9% and 42.6%, respectively; Fisher's exact test; p = .82). The primary tumor was a microcarcinoma (1 cm or less) in 32 patients (38.5%). Positive central compartment node metastases were detected in 31.3% of patients with microcarcinomas, compared with 47.1% of patients with tumors greater than 1 cm. CONCLUSION Younger and older patients had approximately equal rates of central compartment lymph node metastasis. There was also a similar rate of metastasis between microcarcinomas and larger tumors. Our results document that central compartment lymph node dissection is a safe operation and may decrease the need for further operations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Is Prophylactic Central Compartment Lymph Node Dissection Necessary for Papillary Thyroid Carcinoma? Is Prophylactic Central Compartment Lymph Node Dissection Necessary for Papillary Thyroid Carcinoma?

The need for prophylactic central compartment lymph node dissection in patients with papillary thyroid carcinoma continues to be a subject of ongoing debate. Regional lymph node metastases are a common finding with papillary thyroid carcinoma, with an incidence as high as 50% or more. With the widespread use of high resolution ultrasound and sensitive thyroglobulin assays, lymph node metastases...

متن کامل

Squamous Cell Differentiation in Metastatic Papillary Thyroid Carcinoma: Metaplastic

Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1)  and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...

متن کامل

Lymph node dissection in papillary thyroid carcinoma.

The management of papillary thyroid carcinoma continues to evolve. Although the debate over the extent of thyroidectomy has largely faded, the role of elective neck dissection in the surgical management of papillary thyroid cancer has become a topic of contention. The current standard of care for patients with papillary thyroid cancer includes total thyroidectomy and a therapeutic lymph node di...

متن کامل

Optimal surgical extent of lateral and central neck dissection for papillary thyroid carcinoma located in one lobe with clinical lateral lymph node metastasis

BACKGROUND The indications and extent of cervical lymph node dissection in papillary thyroid carcinoma (PTC) are still being debated. The aim of this study was to analyze the patterns of cervical lymph node metastasis in the lateral and central compartment and related factors and suggest the optimal extent of lateral and central neck dissection for PTC patients with clinical lateral lymph node ...

متن کامل

The importance of central compartment elective lymph node excision in the staging and treatment of papillary thyroid cancer.

OBJECTIVE To determine the incidence of nodal involvement and assess the role of elective lymph node (LN) exploration and/or dissection in staging of tumors and treatment of patients with papillary thyroid cancer. DESIGN Retrospective medical chart review. SETTING Academic tertiary care medical center. PATIENTS One hundred patients diagnosed with papillary thyroid cancer by fine-needle as...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Head & neck

دوره 34 2  شماره 

صفحات  -

تاریخ انتشار 2012